Human Longevity Inc..

What HLI actually is

Human Longevity Inc. is the institutional pioneer of the genome-plus-MRI executive health model — co-founded by J. Craig Venter and Peter Diamandis in 2013, well before the current longevity-clinic boom. Its flagship clinic is in San Diego; a second site in South San Francisco opened in 2022.

The programme line-up has been restructured. Executive Health ($8,000, for under-65s) is the single comprehensive day of diagnostics. 100+ Care ($12,000 a year) and 100+ Concierge ($19,000 a year) wrap that diagnostic in a membership with quarterly clinician reviews. A genome-only product, Genomics for All, costs $599. The medical practice behind all of it has been refined across a decade of patient data, which is the longest run in this directory.

What you get

Whole-body MRI with AI analysis, plus brain MRI with NeuroQuant volumetrics. Whole-genome sequencing — actual short-read whole-genome, not a SNP chip. 120+ biomarkers, echocardiogram, EKG, low-dose lung CT and body composition. The 100+ memberships add continuous glucose monitoring, a Zio cardiac patch, Cologuard and cardiac MRI; Concierge adds the GRAIL multi-cancer test and AMRA body-composition MRI. MRI reads are AI-augmented with radiologist sign-off.

The genomics work, ten years in, sits at a depth few competitors match: variant-level annotation against curated longevity-relevant gene sets, clinical correlation rather than consumer-grade reporting, and an institutional dataset deep enough to do meaningful population-level comparison.

On the model

HLI started as a diagnostic clinic and still sells Executive Health as one: the visit is the product. The 100+ memberships add quarterly reviews, concierge primary care and in-house specialist consults — a membership revenue line rather than a treatment franchise. We have not seen the structural treatment-ladder pattern at HLI that we see at the membership concierge clinics; the long-term financial model is the diagnostic itself plus enterprise contracts on the genomics side.

This is the right structure for an editorially sound diagnostic practice and is the reason HLI ranks meaningfully ahead of clinics with comparable diagnostic depth but heavier in-house treatment programmes.

Where it falls short

Three honest caveats.

Two sites, both in California. If you are not on the US West Coast, this is a flight, accommodation, and a day. The visit is worth the trip; planning it as a destination day is the right framing.

Brand surface is muted. HLI does not market like Fountain Life and does not have Peter Attia’s editorial reach. The practice is quieter than the field around it; readers who haven’t gone looking for HLI may have heard about every other major US clinic first.

The genomic data, while the deepest in the field, has the same 2026-stage limitation everyone faces: variant-to-action mapping is sparser than the marketing across the category implies. HLI is honest about this; the deeper question is what your $8,000 finding actually changes about your protocol.

The verdict

For the US-based reader who wants a single decisive diagnostic day with the strongest genomics back-end currently available, HLI is the well-tenured choice. The price is comparable to YEARS Evolve in Berlin; the geography is the operative variable.

A clinic that has been refining the same diagnostic since 2013 is, in 2026, a quieter asset than a brand-new launch. We weight tenure.

Questions readers ask about Human Longevity Inc.

— 01

How much does Human Longevity Inc. cost?

Pricing for Human Longevity Inc., as checked in September 2026: Executive Health at $8,000 per visit; 100+ Care at $12,000 per year; 100+ Concierge at $19,000 per year.

— 02

Does Human Longevity Inc. earn from the treatments it recommends?

Only to a limited degree, in our assessment. Executive Health is a diagnostic visit. The 100+ Care and Concierge memberships add quarterly clinician reviews, concierge primary care and in-house specialist consults; the membership is the revenue line, and HLI does not run a packaged protocol ladder. Human Longevity Inc. scores 21/25 on conflict freedom.

— 03

Is Human Longevity Inc. physician-led?

Yes. Medical leadership: Dr. Tina Ziainia, MD, FACOG (President & Chief Medical Officer). Human Longevity Inc. scores 22/25 on medical supervision.

— 04

How does Human Longevity Inc. rank among longevity clinics?

Human Longevity Inc. ranks #4 of 19 in the 2026 Longevity Clinics ranking, with 88/100 (Excellent). The thoughtful, well-tenured choice. Less brand than Fountain Life, more methodological depth than most.