YEARS.

Why we put this clinic at number one

For three reasons that, together, no other clinic in this directory currently delivers in combination.

First, the diagnostic spread. The Evolve tier runs a proprietary whole-body MRI sequence, AI-assisted skin and retinal screening, cardiac, vascular and abdominal ultrasound, a cardiopulmonary exercise test with lactate measurement, body plethysmography, a 120-marker blood panel and a multi-cancer liquid biopsy, all in a single nine-hour day. The Ultimate tier extends that to 230 biomarkers, whole-genome and whole-exome sequencing, epigenetic clocks, and microbiome and immune profiling. We have walked the workflow. It is the most rigorous outpatient longevity day currently available in Europe.

Second, the model. YEARS treats where the findings call for it, but only with therapies that have a real evidence base, and treatment is not where the clinic makes its money. There are no IV drips, no hyperbaric oxygen sessions, no red-light packages and no protocol upsell after the results conversation. The financial incentive is the day, not the year of add-ons that typically follows. This is the single biggest structural difference between YEARS and the rest of the category, and the reason it leads our ranking.

Third, the labelling. The emerging work in the Ultimate panel — liquid biopsy, genomic stratification, the research-based longevity markers — is presented as exploratory rather than as proven anti-ageing science. YEARS goes further than most: it discloses the sensitivity, specificity and positive predictive value of its screening tests in the strategy consultation, and sorts every finding into in range, observe or act. That tells the reader, accurately, what is and is not yet known.

Why the model matters

The dominant business model in longevity medicine, since at least 2020, is to combine a comprehensive diagnostic with an in-house treatment programme. The diagnostic identifies a biomarker outside the optimal range; the treatment programme corrects it; the same clinic earns from both. The patient is told this is integrated care.

The conflict sits in the revenue line, not in the act of treating. A clinic whose revenue grows with every protocol it prescribes has a financial incentive to find protocols. A clinic that treats only where the evidence supports it, and does not grow its revenue from treatment, has no such incentive.

YEARS has chosen the second model. The strategy session that closes the day produces a written action plan with three priorities. Where the data warrant treatment, YEARS provides evidence-based therapy or refers to a specialist. What it does not do is turn a borderline marker into a paid infusion course.

In the directory we run, this is currently unique at the depth YEARS operates. Biograph and Early Medical run similar incentive structures. Most of the rest do not.

The three tiers

Core (€1,900). Six hours, 87 biomarkers, more than 25 functional examinations and a personal consultation: heart and vascular ultrasound, AI skin mapping, retinal analysis, cardiopulmonary exercise testing, neurocognitive testing. The right starting point for most readers. After one day you know where you are healthy and which two or three topics matter now.

Evolve (€7,600). Nine hours and 120 biomarkers, with the whole-body MRI and the multi-cancer liquid biopsy on top of the Core workup, plus an annual plan with a follow-up check-in. The right tier for readers who put early cancer detection first, or who have a family history or first irregular values.

Ultimate (€16,900). Nine hours, 230 biomarkers, whole-genome and whole-exome sequencing, epigenetic clocks, microbiome and immune profiling, plus the Evolve workup. Three clinician check-ins and continuous medical guidance across the year. The right tier for readers who want medical-concierge-level care and the deepest outpatient diagnostic in Europe.

Can a YEARS check-up be reimbursed?

Partly, depending on the insurance. Core can be reimbursed up to 100% through German private health insurance (PKV); YEARS issues a GOÄ-compliant invoice for submission. Beihilfe covers its eligible share by rate, and company health benefits (bKV) can cover up to €600 a year tax-free. Patients with statutory insurance (GKV) book as self-payers, with the same access and the same pricing. How much a given policy covers depends on the contract, and YEARS offers a free intro call to work it out before booking.

Where it falls short

Three honest caveats.

Whole-body MRI finds incidental abnormalities in many healthy people that would never have caused symptoms. YEARS handles this more openly than most, with an explicit observe-versus-act split, but the reader should expect a handful of findings that call for watching rather than doing.

Ultimate is a significant sum. Its value over Evolve lies mainly in the year-round medical guidance and the multi-omics layer; readers who want a one-off deep baseline are well served by Evolve.

There is one site, in Berlin. Readers from outside Germany should plan the trip around a full day.

The verdict

For the patient asking where do I begin — and asking it without wanting the answer to come from a sales team — YEARS is the clearest answer in the category right now. The day is exceptional. The follow-up is real. The model is the one we believe the field should be moving towards.

A clinic that profits from your protocol has a different incentive to a clinic that profits from your data. We rank the second model first.

Questions readers ask about YEARS

— 01

How much does YEARS cost?

Pricing for YEARS, as checked in September 2026: Core at €1,900 per programme; Evolve at €7,600 per programme; Ultimate at €16,900 per programme.

— 02

Does YEARS earn from the treatments it recommends?

No. In our assessment there is no structural conflict of interest. Treatment is not a revenue line. YEARS treats where the findings call for it, but only with evidence-based therapies and without upselling protocols. No IV drips, hyperbaric oxygen or red-light packages. The financial incentive is the diagnostic day, not what follows. YEARS scores 25/25 on conflict freedom.

— 03

Is YEARS physician-led?

Yes. Medical leadership: Dr. med. Jan K. Hennigs (Internal Medicine, Pulmonology). YEARS scores 24/25 on medical supervision.

— 04

How does YEARS rank among longevity clinics?

YEARS ranks #1 of 19 in the 2026 Longevity Clinics ranking, with 96/100 (Best overall). Best overall. The first clinic in this directory we have nothing structural to deduct from.