Aviv Clinics.
Hyperbaric oxygen, Efrati's research, three-month protocol.
| Axis | Points | |
|---|---|---|
| Diagnostic depth | 17/25 | |
| Medical supervision | 21/25 | |
| Conflict freedom | 14/25 | |
| Evidence base | 19/25 | |
| Composite | 71/100 |
Diagnose-and-treat under one roof. The proprietary Hyperoxic-Hypoxic Paradox HBOT protocol is the central revenue line, and the diagnostic intake (SPECT scans, cognitive batteries, biomarkers) feeds patients into an eight- to twelve-week daily HBOT programme at the same clinic.
Dr. Shai Efrati publishes the underlying HBOT research in peer-reviewed journals and is direct about the trial-grade nature of the cognitive-performance claims. Marketing occasionally runs ahead of the published outcomes.
Not currently bookable at its Florida site, which closed in April 2026. The protocol answers a specific cognitive question, not a general longevity baseline.
Tiers and prices
| Tier | Price | Included |
|---|---|---|
| Performance Base (8 weeks) | $18,214 per programme | Published on aviv-clinics.com; may no longer be offered after the Florida closure |
| Recovery Premium (12 weeks) | $53,146 per programme | Adds physical, speech and occupational therapy · published price, availability unclear |
Prices are the clinic’s own published figures at the date above, exclusive of travel and accommodation unless the tier note says otherwise. We take no commission on any booking.
Status update, September 2026
A public notice dated 3 April 2026 announced that Aviv Villages LLC, doing business as Aviv Clinic, would close its clinic in The Villages, Florida, on or about 24 April 2026. OxyPeak Longevity Institute now operates at the same address on Brownwood Boulevard. Aviv’s own website still lists the Florida programme and its prices. The former Dubai site now operates as The Brain & Performance Centre, a DP World company, and Aviv’s Israeli connection is a partnership with the Sagol Center at Shamir Medical Center rather than an Aviv clinic. We keep this profile as a reference for the protocol; it is not currently bookable at the Florida site.
What Aviv actually is
A focused product, not a general longevity practice. Aviv Clinics — run until April 2026 from The Villages, Florida — is built around one therapy: hyperbaric oxygen, delivered in Dr. Shai Efrati’s Hyperoxic-Hypoxic Paradox protocol over an eight- or twelve-week course of two-hour daily sessions. Dr. Amir Hadanny is Chief Medical Officer; Efrati chairs the medical advisory board.
Efrati is the most-published HBOT researcher in the field. The protocol he runs at Aviv has its own clinical-trial dataset behind it. The research foundation, in our reading, is real.
The clinical product around the HBOT is what makes Aviv a longevity clinic rather than a hyperbaric centre: cognitive training during sessions, physical training between sessions, nutrition coaching, structured diagnostic intake, and follow-up out to five years. The frame is cognitive performance and age-related decline, not general longevity baselining.
What you get
The diagnostic intake is unusually deep on the cognitive axis. SPECT scans for cerebral perfusion mapping. A cognitive assessment battery that goes well beyond the typical executive workup. Brain MRI, and pTau in the Recovery tracks — a relevant Alzheimer’s risk marker that most longevity clinics don’t run. Plus a cardiopulmonary exercise test, EKG, gait analysis, body composition and standard biomarker testing.
For a patient with specific cognitive concerns — post-concussion recovery, age-related cognitive decline, family history of dementia — this is the workup that matches the question.
The treatment programme is the centre of gravity: two-hour daily HBOT sessions across eight or twelve weeks, in a multi-place chamber, with the proprietary protocol that alternates hyperoxic and hypoxic phases. Published prices run from $18,214 (Performance Base, eight weeks) to $53,146 (Recovery Premium, twelve weeks, with physical, speech and occupational therapy). Until the Florida closure, patients commuted to The Villages or stayed locally for the duration.
Where the evidence question lives
HBOT for clinical indications — post-stroke recovery, post-concussion, certain ulcer healing, decompression illness — has a robust literature behind it. HBOT for healthy-population longevity, the broader claim Aviv’s marketing sometimes implies, is less well-established.
Efrati’s clinical trials have shown promising signals on cognitive and biomarker outcomes in specific populations, and the publications are real. The gap between trial-grade outcomes in defined populations and cognitive performance enhancement in healthy adults is the gap a reader needs to understand before committing to the cheque.
We credit Aviv for publishing the research and being direct about the trial-grade framing in clinical conversation. We deduct points where the marketing copy outruns the published outcomes.
On the model
This is the cleanest example of the diagnose-then-treat conflict pattern in our directory. The diagnostic intake — at substantial cost — feeds directly into an eight- to twelve-week daily HBOT programme at the same clinic. There is no editorial separation between the workup that finds the indication and the practice that bills for the protocol that addresses it.
Aviv is, in our experience, not aggressive on this — clinicians who have decided a patient is not a candidate have said so. But the structural geometry is what it is, and the score reflects it.
Where Aviv is the right answer
For a specific reader profile, Aviv earns the visit.
The patient with diagnosed mild cognitive impairment, post-concussion symptoms, or significant family history of dementia, looking for a research-backed three-month protocol with structured measurement before and after. The diagnostic intake matches the question, the treatment has a published evidence base for that indication, and the multi-week commitment delivers what it claims.
For the reader looking for a general longevity baseline, Aviv is not it. The diagnostic spread is too cognitive-focused, and the treatment funnel is too narrow, to serve as a starting point.
The verdict
A specialist product, well-executed, with a structural conflict that we score honestly. If the cognitive question is yours, this is the directory’s strongest match. If it isn’t, the diagnostic-led generalist clinics (YEARS, Biograph, Human Longevity Inc.) are better starting points.
A clinic with one therapy and real research behind it is structurally different from a clinic with many therapies and thinner research behind any of them. Both can earn the price for the right patient.
Questions readers ask about Aviv Clinics
— 01 How much does Aviv Clinics cost?
Pricing for Aviv Clinics, as checked in September 2026: Performance Base (8 weeks) at $18,214 per programme; Recovery Premium (12 weeks) at $53,146 per programme.
— 02 Does Aviv Clinics earn from the treatments it recommends?
Yes. We score this as a structural conflict of interest. Diagnose-and-treat under one roof. The proprietary Hyperoxic-Hypoxic Paradox HBOT protocol is the central revenue line, and the diagnostic intake (SPECT scans, cognitive batteries, biomarkers) feeds patients into an eight- to twelve-week daily HBOT programme at the same clinic. Aviv Clinics scores 14/25 on conflict freedom.
— 03 Is Aviv Clinics physician-led?
Yes. Medical leadership: Dr. Amir Hadanny, MD, PhD (Chief Medical Officer); Prof. Shai Efrati (Founder, Chairman of the Medical Advisory Board). Aviv Clinics scores 21/25 on medical supervision.
— 04 How does Aviv Clinics rank among longevity clinics?
Aviv Clinics ranks #17 of 19 in the 2026 Longevity Clinics ranking, with 71/100 (Good, with caveats). Not currently bookable at its Florida site, which closed in April 2026. The protocol answers a specific cognitive question, not a general longevity baseline.