HUM2N Mayfair.

What HUM2N actually is

A functional-medicine practice that speaks the longevity dialect fluently — and then, unusually for London, has the regulatory standing to actually prescribe the protocols it diagnoses. Hormone replacement, peptides, off-label medications: HUM2N’s clinicians do them, calmly, where most competitors hand you a list and a cab.

That capability is the substantive reason to consider them. Not the Mayfair address.

The day

The £4,800 baseline buys a five-hour appointment block: bloodwork, DEXA, VO₂ max, doctor consultation, protocol design. Hormone-panel work is more comprehensive than the European median — they take saliva and urine alongside blood, which most clinics don’t bother to do.

What’s missing is significant: no whole-body MRI on site. For imaging, you are referred to The London Clinic, fifteen minutes north, at additional expense. If imaging is what brought you to longevity medicine, HUM2N is not the right starting point.

The hormone conversation

This is where HUM2N earns its keep. London is a difficult city to find a clinician comfortable with bioidentical HRT, off-label TRT, or growth-hormone-releasing peptide protocols. HUM2N’s medical director runs them, with documented protocols and structured follow-up at six and twelve weeks.

Whether you should want these protocols is a separate question — and one the clinic, to its credit, will sometimes answer in the negative. We watched a forty-two-year-old in good metabolic health be talked out of a TRT trial. That’s a competent clinic.

Membership versus day-rate

The £420/month membership is the sensible structure. It includes monthly clinician contact, quarterly bloodwork, and discounted infusions. For anyone planning a six-to-twelve-month protocol, the per-month cost beats the day-rate framing meaningfully.

For a one-shot survey-the-system visit, however, you get more breadth elsewhere — see YEARS Evolve for that profile.

The verdict

HUM2N is the right clinic if you have a specific question — should I be on testosterone, can my mid-forties fatigue be diagnosed, what protocol survives twelve months — and want it answered, dispensed and reviewed under one roof. It is the wrong clinic if you want the full diagnostic spread, particularly imaging.

The clinic that prescribes is a different proposition to the clinic that recommends. Both are useful. Buy the right one.